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CS-W001157 4
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Methyl 4-(2-aminoacetyl)benzoate hydrochloride

  • CAS No. 860344-26-9

  • Cat. No. CS-0374570
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 4-(2-aminoacetyl)benzoate hydrochloride|CS-0374570

Structure of 860344-26-9

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General Information

  • CAS No. 860344-26-9
  • Cat. No. CS-0374570
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂ClNO₃
  • Molecular Weight None
  • Synonym(s) 4-(2-Amino-acetyl)-benzoic acid methyl ester hydrochloride
  • SMILES O=C(OC)C1=CC=C(C(CN)=O)C=C1.[H]Cl

Description

Methyl 4-(2-aminoacetyl)benzoate hydrochloride features a strategically positioned aminoacetyl group that enhances solubility and reactivity in peptide coupling workflows. This bench-stable derivative integrates readily into synthetic sequences requiring polar, nitrogen-rich intermediates. The hydrochloride salt form ensures improved handling and storage stability.

Application

Methyl 4-(2-aminoacetyl)benzoate hydrochloride serves as a versatile building block in medicinal chemistry, enabling direct access to substituted benzamide scaffolds. The aminoacetyl group facilitates efficient derivatization via acylation, alkylation, or cyclization reactions, while the methyl ester offers compatibility with standard reduction and amidation protocols. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step syntheses of bioactive heterocycles and API intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   69.39
  • LogP   1.0364
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   3

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