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CS-W001157 4
Total: USD 88.00

7-Bromo-4-hydroxyquinoline-3-carboxylic acid

  • CAS No. 860205-92-1

  • Cat. No. CS-0131701
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

7-Bromo-4-hydroxyquinoline-3-carboxylic acid|CS-0131701

Structure of 860205-92-1

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Description

7-Bromo-4-hydroxyquinoline-3-carboxylic acid features a rigid quinoline core functionalized with bromine, hydroxyl, and carboxylic acid groups at key positions. This combination enables direct coupling in cross-coupling reactions and facilitates conjugation to biomolecules. The electron-deficient quinoline scaffold enhances reactivity in transition-metal-catalyzed transformations, while the bench-stable hydroxyl and carboxylic acid moieties support straightforward derivatization under standard conditions.

Application

7-Bromo-4-hydroxyquinoline-3-carboxylic acid serves as a versatile building block for the synthesis of quinoline-based pharmaceutical intermediates. Its well-defined functional group array—bromine at C7, hydroxyl at C4, and carboxylic acid at C3—enables diverse transformations including Suzuki-Miyaura coupling, nucleophilic substitution, and esterification. The compound exhibits good bench stability and facilitates straightforward purification, making it suitable for both medicinal chemistry screening and process development workflows.

General Information

  • CAS No. 860205-92-1
  • Cat. No. CS-0131701
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₆BrNO₃
  • Molecular Weight 268.06
  • Synonym(s) 7-bromo-4-oxo-1H-quinoline-3-carboxylic acid
  • SMILES BrC1=CC=C(C(O)=C(C=N2)C(O)=O)C2=C1

Computational Chemistry Data

  • TPSA   70.42
  • LogP   2.4011
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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