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Structure of 860205-92-1
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7-Bromo-4-hydroxyquinoline-3-carboxylic acid features a rigid quinoline core functionalized with bromine, hydroxyl, and carboxylic acid groups at key positions. This combination enables direct coupling in cross-coupling reactions and facilitates conjugation to biomolecules. The electron-deficient quinoline scaffold enhances reactivity in transition-metal-catalyzed transformations, while the bench-stable hydroxyl and carboxylic acid moieties support straightforward derivatization under standard conditions.
7-Bromo-4-hydroxyquinoline-3-carboxylic acid serves as a versatile building block for the synthesis of quinoline-based pharmaceutical intermediates. Its well-defined functional group array—bromine at C7, hydroxyl at C4, and carboxylic acid at C3—enables diverse transformations including Suzuki-Miyaura coupling, nucleophilic substitution, and esterification. The compound exhibits good bench stability and facilitates straightforward purification, making it suitable for both medicinal chemistry screening and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: