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CS-W001157 4
Total: USD 88.00

(4-(Cyclopropylcarbamoyl)phenyl)boronic acid

  • CAS No. 860173-33-7

  • Cat. No. CS-0157614
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(4-(Cyclopropylcarbamoyl)phenyl)boronic acid|CS-0157614

Structure of 860173-33-7

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General Information

  • CAS No. 860173-33-7
  • Cat. No. CS-0157614
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂BNO₃
  • Molecular Weight 205.02
  • Synonym(s) 4-(CyclopropylcarbaMoyl)phenylboronic Acid
  • SMILES C1=C(C=CC(=C1)B(O)O)C(=O)NC2CC2

Description

This boronate moiety integrates a cyclopropylcarbamoyl group at the para position, delivering enhanced stability and solubility. The scaffold enables efficient Suzuki-Miyaura coupling under mild conditions, facilitating rapid access to biaryl architectures in medicinal chemistry and materials synthesis.

Application

(4-(Cyclopropylcarbamoyl)phenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. The ortho-substituted arylboronic acid exhibits good bench stability and functional group tolerance, facilitating downstream derivatization in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   69.56
  • LogP   -0.7414
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   3

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