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CS-W001157 4
Total: USD 88.00

1-Phenyl-2-(triphenylphosphoranylidene)ethanone

  • CAS No. 859-65-4

  • Cat. No. CS-0156573
  • Molecule weight380.42
  • Purity≥98%
  • MDL No.MFCD00014088

*For research and further manufacturing use only, not for direct human use.

1-Phenyl-2-(triphenylphosphoranylidene)ethanone|CS-0156573

Structure of 859-65-4

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General Information

  • CAS No. 859-65-4
  • Cat. No. CS-0156573
  • Purity ≥98%
  • MDL No. MFCD00014088
  • Storage 4°C, stored under nitrogen, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₆H₂₁OP
  • Molecular Weight 380.42
  • Synonym(s) Benzoylmethylenetriphenylphosphorane
  • SMILES C1=CC=C(C=C1)C(=O)C=P(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4

Description

1-Phenyl-2-(triphenylphosphoranylidene)ethanone is a stable, bench-ready Wittig reagent featuring a phosphorus-stabilized ylide with enhanced reactivity. This electron-rich species enables efficient olefination of aldehydes and ketones under mild conditions, delivering (E)-alkenes with high selectivity. The triphenylphosphine moiety ensures good solubility in common organic solvents and facilitates clean reaction profiles.

Application

1-Phenyl-2-(triphenylphosphoranylidene)ethanone serves as a stable, bench-ready ylide reagent for the synthesis of substituted alkenes via Wittig-type olefination. Its well-documented reactivity enables efficient conversion of aldehydes and ketones into (E)- or (Z)-configured enones with predictable stereochemistry. The triphenylphosphine oxide byproduct is easily removed during workup, facilitating purification and making it ideal for scalable laboratory applications in complex molecule assembly.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P280-P304+P340-P405-P501

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   4.6656
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   5

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