(2-Bromopyridin-4-yl)methanamine

Name: (2-Bromopyridin-4-yl)methanamine
Brand: ChemScene
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CAS No. 858362-82-0
Cat. No. CS-0042745
Purity≥95%
MDL No.MFCD07367880

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(2-Bromopyridin-4-yl)methanamine|CS-0042745

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General Information

CAS No. 858362-82-0
Cat. No. CS-0042745
Purity ≥95%
MDL No. MFCD07367880
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₇BrN₂
Molecular Weight 187.04
Synonym(s) 4-pyridinemethanamine, 2-bromo-
SMILES NCC1=CC(Br)=NC=C1

Description

This bench-stable amine features a pyridyl nitrogen and a bromomethyl group, enabling direct functionalization in cross-coupling reactions. The para-brominated scaffold supports rapid derivatization, integrating seamlessly into synthetic pathways for bioactive molecules and advanced materials.

Application

(2-Bromopyridin-4-yl)methanamine serves as a versatile building block for constructing pyridine-based heterocycles and pharmaceutical intermediates. Its bromo group enables palladium-catalyzed cross-coupling reactions, while the primary amine facilitates derivatization via acylation, alkylation, or condensation. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 38.91
LogP 1.3028
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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(2-Bromopyridin-4-yl)methanamine

CAS No. 858362-82-0

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