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Structure of 858121-94-5
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4-(Bromomethyl)-1,1-difluorocyclohexane features a reactive bromomethyl group tethered to a cyclohexane ring bearing two fluorine atoms at the same carbon. This configuration imparts enhanced stability and polarity, facilitating efficient incorporation into complex molecular architectures under mild conditions. The difluoromethyl moiety enhances metabolic resistance and modulates lipophilicity, making this compound valuable for medicinal chemistry applications requiring robust functionalization.
4-(Bromomethyl)-1,1-difluorocyclohexane serves as a versatile difluorocyclohexyl building block for C–C and C–heteroatom bond formation. The bromomethyl group enables facile nucleophilic substitution, while the 1,1-difluoro substituent imparts enhanced metabolic stability and lipophilicity. Its bench-stable nature and compatibility with standard coupling protocols facilitate efficient integration into complex molecular architectures, including bioactive heterocycles and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: