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CS-W001157 4
Total: USD 88.00

7-(Hydroxymethyl)-3,4-dihydroquinolin-2(1H)-one

  • CAS No. 857272-53-8

  • Cat. No. CS-0066693
  • Molecule weight177.20
  • Purity≥95%
  • MDL No.MFCD13179402

*For research and further manufacturing use only, not for direct human use.

7-(Hydroxymethyl)-3,4-dihydroquinolin-2(1H)-one|CS-0066693

Structure of 857272-53-8

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General Information

  • CAS No. 857272-53-8
  • Cat. No. CS-0066693
  • Purity ≥95%
  • MDL No. MFCD13179402
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₁NO₂
  • Molecular Weight 177.20
  • Synonym(s) 3,4-dihydro-7-(hydroxymethyl)-2(1H)-Quinolinone
  • SMILES O=C1NC2=C(C=CC(CO)=C2)CC1

Synthesis

  • Route1
    • Ethyl 2-oxo-1,2,3,4-tetrahydroquinoline-7-carboxylate|CS-0968801
      697306-33-5
    • ~21%
    • In-stock
      7-(Hydroxymethyl)-3,4-dihydroquinolin-2(1H)-one|CS-0066693
      857272-53-8

    References

    • REVIVA PHARMACEUTICALS, INC. Patent: US2008/293736 A1, 2008 ; Location in patent: Page/Page column 30 ; US 20080293736 A1
  • Route2
    • 2-Oxo-1,2,3,4-tetrahydroquinoline-7-carbaldehyde|CS-0380566
      917836-04-5
    • ~%
    • In-stock
      7-(Hydroxymethyl)-3,4-dihydroquinolin-2(1H)-one|CS-0066693
      857272-53-8

    References

    • TAISHO PHARMACEUTICAL CO., LTD.; KANUMA, Kosuke; MIYAKOSHI, Naoki; KAWAMURA, Madoka; SHIBATA, Tsuyoshi Patent: WO2010/38901 A1, 2010 ; Location in patent: Page/Page column 70-71 ; WO 2010/038901 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.33
  • LogP   1.0636
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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