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CS-W001157 4
Total: USD 88.00

(R)-2-Amino-2-cyclohexylethan-1-ol

  • CAS No. 85711-13-3

  • Cat. No. CS-0088060
  • Purity≥97%
  • MDL No.MFCD04112588

*For research and further manufacturing use only, not for direct human use.

(R)-2-Amino-2-cyclohexylethan-1-ol|CS-0088060

Structure of 85711-13-3

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General Information

  • CAS No. 85711-13-3
  • Cat. No. CS-0088060
  • Purity ≥97%
  • MDL No. MFCD04112588
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₇NO
  • Molecular Weight 143.23
  • Synonym(s) D-Cyclohexylglycinol
  • SMILES N[C@H](C1CCCCC1)CO

Description

(R)-2-Amino-2-cyclohexylethan-1-ol is a chiral building block featuring a primary amine and hydroxyl group on a cyclohexyl-substituted ethane backbone. This configuration enables stereoselective synthesis in medicinal chemistry, particularly for bioactive molecules requiring defined spatial orientation. The molecule exhibits favorable solubility and stability under standard bench conditions, facilitating straightforward handling in process development workflows.

Application

(R)-2-Amino-2-cyclohexylethan-1-ol serves as a chiral building block for synthesizing bioactive molecules, leveraging its pendant primary alcohol and secondary amine for orthogonal functionalization. The molecule exhibits bench stability and facilitates efficient derivatization in standard peptide and medicinal chemistry workflows. Its defined stereochemistry enables predictable stereoselective transformations, making it a reliable scaffold for heterocyclic and API intermediates requiring controlled spatial orientation.

Synthesis

  • Route1

    References

    • Devant, Ralf; Braun, Manfred Chemische Berichte, 1986 , vol. 119, # 7 p. 2191 - 2207
  • Route2
    • H-D-Phg-OH Ampicillin Impurity|CS-0229771
      875-74-1
    • ~%
    • In-stock
      (R)-2-Amino-2-cyclohexylethan-1-ol|CS-0088060
      85711-13-3

    References

    • Chemische Berichte, , vol. 119, # 7 p. 2191 - 2207

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   0.8863
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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