Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-Bromo-2-chloro-5-nitro-6-picoline

  • CAS No. 856834-95-2

  • Cat. No. CS-0019331
  • Purity≥98%
  • MDL No.MFCD09839270

*For research and further manufacturing use only, not for direct human use.

3-Bromo-2-chloro-5-nitro-6-picoline|CS-0019331

Structure of 856834-95-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 856834-95-2
  • Cat. No. CS-0019331
  • Purity ≥98%
  • MDL No. MFCD09839270
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄BrClN₂O₂
  • Molecular Weight 251.47
  • Synonym(s) 3-Bromo-2-chloro-6-methyl-5-nitropyridine
  • SMILES O=[N+](C1=C(C)N=C(Cl)C(Br)=C1)[O-]

Description

3-Bromo-2-chloro-5-nitro-6-picoline features a densely functionalized pyridine core with orthogonal halogen and nitro substituents. This electron-deficient heterocycle enables selective cross-coupling reactions under palladium catalysis, serving as a key intermediate in the synthesis of advanced pharmaceutical scaffolds and bioactive nitrogen-containing compounds.

Application

3-Bromo-2-chloro-5-nitro-6-picoline serves as a versatile building block for heterocyclic synthesis, enabling sequential functionalization via cross-coupling and nucleophilic substitution. Its complementary halogenation pattern facilitates selective transformations under palladium-catalyzed conditions, while the nitro group provides a handle for reduction and subsequent cyclization. Bench-stable and compatible with standard purification protocols, it supports efficient access to complex nitrogen-containing scaffolds relevant in medicinal chemistry and agrochemical development.

Synthesis

  • Route1

    References

    • SYNGENTA PARTICIPATIONS AG; SYNGENTA LIMITED Patent: WO2008/101682 A2, 2008 ; Location in patent: Page/Page column 42-43 ;
  • Route2

    References

    • Parker; Shive Journal of the American Chemical Society, 1947 , vol. 69, p. 63,66
  • Route3
    • null|null
      109-06-8
    • ~%
    • In-stock
      3-Bromo-2-chloro-5-nitro-6-picoline|CS-0019331
      856834-95-2

    References

    • Parker; Shive Journal of the American Chemical Society, 1947 , vol. 69, p. 63,66

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H318
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   56.03
  • LogP   2.71412
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 3-Bromo-2-chloro-5-nitro-6-picoline sigma3-Bromo-2-chloro-5-nitro-6-picoline manufacturer3-Bromo-2-chloro-5-nitro-6-picoline price3-Bromo-2-chloro-5-nitro-6-picoline structure3-Bromo-2-chloro-5-nitro-6-picoline SDSbuy 3-Bromo-2-chloro-5-nitro-6-picoline3-Bromo-2-chloro-5-nitro-6-picoline supplier3-Bromo-2-chloro-5-nitro-6-picoline uses3-Bromo-2-chloro-5-nitro-6-picoline molecular weightprice of 3-Bromo-2-chloro-5-nitro-6-picoline3-Bromo-2-chloro-5-nitro-6-picoline chemical name formula of 3-Bromo-2-chloro-5-nitro-6-picoline
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label