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Structure of 85614-44-4
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4-(Pyrrolidin-1-yl)butanoic acid features a polar pyrrolidine ring linked to a flexible aliphatic chain terminating in a carboxylic acid group. This structure enables hydrogen bonding and enhanced solubility in aqueous and organic media, supporting its use in bioconjugation and peptide derivatization. The molecule integrates readily into molecular scaffolds requiring both hydrophilicity and amine functionality.
4-(Pyrrolidin-1-yl)butanoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive amides and esters through standard coupling protocols. Its aliphatic chain with a terminal carboxylic acid facilitates conjugation with amines, while the pyrrolidine moiety provides moderate basicity and hydrogen-bonding capability. The compound exhibits good bench stability and is compatible with common functional group manipulations, making it valuable for constructing diverse heterocyclic scaffolds and lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: