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CS-W001157 4
Total: USD 88.00

4-(Pyrrolidin-1-yl)butanoic acid

  • CAS No. 85614-44-4

  • Cat. No. CS-0317086
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-(Pyrrolidin-1-yl)butanoic acid|CS-0317086

Structure of 85614-44-4

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Description

4-(Pyrrolidin-1-yl)butanoic acid features a polar pyrrolidine ring linked to a flexible aliphatic chain terminating in a carboxylic acid group. This structure enables hydrogen bonding and enhanced solubility in aqueous and organic media, supporting its use in bioconjugation and peptide derivatization. The molecule integrates readily into molecular scaffolds requiring both hydrophilicity and amine functionality.

Application

4-(Pyrrolidin-1-yl)butanoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive amides and esters through standard coupling protocols. Its aliphatic chain with a terminal carboxylic acid facilitates conjugation with amines, while the pyrrolidine moiety provides moderate basicity and hydrogen-bonding capability. The compound exhibits good bench stability and is compatible with common functional group manipulations, making it valuable for constructing diverse heterocyclic scaffolds and lead optimization campaigns.

General Information

  • CAS No. 85614-44-4
  • Cat. No. CS-0317086
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₅NO₂
  • Molecular Weight 157.21
  • Synonym(s) 1-Pyrrolidinebutanoic acid
  • SMILES C1CCN(C1)CCCC(=O)O

Computational Chemistry Data

  • TPSA   40.54
  • LogP   0.947
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   4

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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