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Structure of 855836-62-3
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2-Bromo-3-chlorophenol features a bromine atom at the ortho position and a chlorine substituent at the meta position relative to the hydroxyl group, creating a uniquely electron-deficient aromatic scaffold. This configuration enhances reactivity in electrophilic substitution and facilitates coupling reactions under mild conditions. The compound exhibits bench-stable handling characteristics and integrates readily into complex synthetic sequences requiring halogen-directed functionalization.
2-Bromo-3-chlorophenol serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling regioselective functionalization via palladium-catalyzed cross-coupling reactions. Its ortho-halogenated structure provides excellent compatibility with standard Suzuki, Stille, and Negishi transformations, while the phenolic hydroxyl group allows for derivatization or protection under mild conditions. Bench-stable and readily purified by recrystallization, it functions as a key intermediate in the construction of complex heterocyclic scaffolds and bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: