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Structure of 853909-08-7
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5-Ethynyl-2-fluoropyridine features a reactive alkyne group conjugated to an electron-deficient fluoropyridine ring, enabling efficient copper-catalyzed azide-alkyne cycloaddition. This combination delivers high chemoselectivity and stability under standard conditions, making it ideal for bioconjugation and probe synthesis in chemical biology workflows.
5-Ethynyl-2-fluoropyridine serves as a versatile building block in transition-metal-catalyzed coupling reactions, enabling efficient access to substituted pyridine scaffolds. Its orthogonal reactivity profile—combining a terminal alkyne with an electrophilic fluorinated pyridine ring—facilitates modular synthesis of functionalized heterocycles. The compound exhibits excellent bench stability and compatibility with standard reaction conditions, supporting straightforward purification and integration into complex molecular architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: