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Structure of 851784-82-2
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This tetrahydroisoquinoline derivative features a tert-butoxycarbonyl-protected amine, two chloro substituents at the 5 and 7 positions, and a carboxylic acid group at the 6-position. The molecule integrates readily into synthetic sequences requiring selective functionalization and stability under standard bench conditions.
Serves as a versatile building block for the synthesis of isoquinoline-based pharmaceutical intermediates. The tert-butyl carbamate group enables convenient protection and deprotection under mild acidic conditions, while the dichloro substitution pattern enhances metabolic stability and provides a defined electronic profile. The carboxylic acid functionality facilitates direct coupling reactions or derivatization, offering high bench stability and ease of purification in multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: