8-Boc-2,8-Diazaspiro[4.5]decane hydrochloride

Name: 8-Boc-2,8-Diazaspiro[4.5]decane hydrochloride
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 851325-42-3
Cat. No. CS-0000481
Purity≥97%
MDL No.MFCD13185062

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

8-Boc-2,8-Diazaspiro[4.5]decane hydrochloride|CS-0000481

Structure of 851325-42-3

Size

Price

Quantity

* Please select Quantity before adding items.

Description

tert-Butyl 2,8-diazaspiro[4.5]decane-8-carboxylate hydrochloride features a rigid spirocyclic scaffold with two nitrogen atoms positioned for efficient coordination and stereocontrol. The tert-butyl ester group enables convenient deprotection under mild acidic conditions, while the hydrochloride salt enhances solubility and stability in protic solvents. This compound serves as a key chiral building block in medicinal chemistry, particularly for constrained heterocycles in targeted drug discovery.

Application

tert-Butyl 2,8-diazaspiro[4.5]decane-8-carboxylate hydrochloride serves as a robust spirocyclic amine building block, enabling efficient access to complex nitrogen-containing scaffolds. The protected diamine functionality exhibits excellent bench stability and orthogonal reactivity, facilitating selective functionalization in multistep synthesis. Its hydrochloride salt form enhances solubility and handling, supporting broad utility in medicinal chemistry campaigns and API development workflows.

General Information

CAS No. 851325-42-3
Cat. No. CS-0000481
Purity ≥97%
MDL No. MFCD13185062
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₃H₂₅ClN₂O₂
Molecular Weight 276.80
Synonym(s) None
SMILES O=C(N1CCC2(CC1)CNCC2)OC(C)(C)C.Cl

Computational Chemistry Data

TPSA 41.57
LogP 2.4188
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Building Blocks Skeleton Spirol Rings compounds

Key Words

851325-42-3 sigma851325-42-3 manufacturer851325-42-3 price851325-42-3 structure851325-42-3 SDSbuy 851325-42-3851325-42-3 supplier851325-42-3 uses851325-42-3 molecular weightprice of 851325-42-3851325-42-3 chemical name formula of 851325-42-3

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

8-Boc-2,8-Diazaspiro[4.5]decane hydrochloride

CAS No. 851325-42-3

Recommended Products