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CS-W001157 4
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(2,5-Difluorophenyl)methanamine

  • CAS No. 85118-06-5

  • Cat. No. CS-W018262
  • Purity≥97%
  • MDL No.MFCD00010143

*For research and further manufacturing use only, not for direct human use.

(2,5-Difluorophenyl)methanamine|CS-W018262

Structure of 85118-06-5

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General Information

  • CAS No. 85118-06-5
  • Cat. No. CS-W018262
  • Purity ≥97%
  • MDL No. MFCD00010143
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇F₂N
  • Molecular Weight 143.14
  • Synonym(s) Benzenemethanamine, 2,5-difluoro
  • SMILES NCC1=C(F)C=CC(F)=C1

Description

(2,5-Difluorophenyl)methanamine features a difluorinated aromatic ring that imparts enhanced metabolic stability and improved membrane permeability. This bench-stable primary amine integrates readily into pharmaceutical scaffolds, serving as a key building block for CNS-targeted therapeutics and bioactive heterocycles.

Application

(2,5-Difluorophenyl)methanamine serves as a versatile building block for medicinal chemistry and agrochemical synthesis, enabling the construction of fluorinated aromatic scaffolds. Its benzylic amine functionality facilitates straightforward derivatization via alkylation, acylation, or reductive amination, while the ortho-fluorine substituents enhance metabolic stability and modulate electronic properties. The compound exhibits good bench stability and compatibility with standard purification techniques, making it well-suited for routine use in multi-step syntheses.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H227-H314
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.4235
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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