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Structure of 850689-27-9
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Methyl 3-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate features a boronate ester group enabling reliable Suzuki-Miyaura cross-coupling under standard conditions. The para-amino substituent offers enhanced reactivity and directs regioselective functionalization. This bench-stable reagent integrates seamlessly into complex molecular architectures requiring nitrogenated heterocyclic motifs.
Methyl 3-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The tetramethylboronate group enables efficient coupling under mild conditions, while the ortho-amino and ester functionalities offer orthogonal reactivity for downstream modifications. Bench-stable and readily purified, it facilitates rapid access to substituted biaryl and heterocyclic scaffolds in medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: