1-(2,4-Difluorophenyl)propan-1-one

Name: 1-(2,4-Difluorophenyl)propan-1-one
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 85068-30-0
Cat. No. CS-W017703
Purity≥98%
MDL No.MFCD00015507

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-(2,4-Difluorophenyl)propan-1-one|CS-W017703

Structure of 85068-30-0

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 85068-30-0
Cat. No. CS-W017703
Purity ≥98%
MDL No. MFCD00015507
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₈F₂O
Molecular Weight None
Synonym(s) 2',4'-Difluoropropiophenone
SMILES CCC(C1=CC=C(F)C=C1F)=O

Description

1-(2,4-Difluorophenyl)propan-1-one features a fluorinated aromatic ring that imparts enhanced metabolic stability and lipophilicity. This ketone serves as a key intermediate in the synthesis of pharmaceuticals targeting CNS disorders, where its electron-deficient aryl moiety facilitates selective coupling reactions under mild conditions.

Application

1-(2,4-Difluorophenyl)propan-1-one serves as a versatile building block in medicinal chemistry, enabling efficient construction of biologically relevant scaffolds. Its difluorophenyl moiety enhances metabolic stability and modulates electronic properties, while the ketone functionality facilitates nucleophilic addition, reductive amination, and enolate-based transformations. The compound exhibits good bench stability and compatibility with standard synthetic protocols, facilitating straightforward incorporation into complex molecular architectures.

Synthesis

Route1
- 372-18-9
- 79-03-8
- ~86%
- In-stock
  
  85068-30-0
References
- Gala, Dinesh; DiBenedetto, Donald J.; Mergelsberg, Ingrid; Kugelman, Max Tetrahedron Letters, 1996 , vol. 37, # 45 p. 8117 - 8120

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362+P364

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 17.07
LogP 2.5575
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Ketone

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

1-(2,4-Difluorophenyl)propan-1-one sigma1-(2,4-Difluorophenyl)propan-1-one manufacturer1-(2,4-Difluorophenyl)propan-1-one price1-(2,4-Difluorophenyl)propan-1-one structure1-(2,4-Difluorophenyl)propan-1-one SDSbuy 1-(2,4-Difluorophenyl)propan-1-one1-(2,4-Difluorophenyl)propan-1-one supplier1-(2,4-Difluorophenyl)propan-1-one uses1-(2,4-Difluorophenyl)propan-1-one molecular weightprice of 1-(2,4-Difluorophenyl)propan-1-one1-(2,4-Difluorophenyl)propan-1-one chemical name formula of 1-(2,4-Difluorophenyl)propan-1-one

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

1-(2,4-Difluorophenyl)propan-1-one

CAS No. 85068-30-0

Recommended Products