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Structure of 850495-91-9
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5-Bromo-2-(tert-butoxy)pyridine features a sterically shielded tert-butoxy group at the 2-position, enhancing stability and solubility in organic media. The electron-deficient pyridine ring pairs with the bromo substituent at C5 to enable efficient coupling reactions. This bench-stable reagent integrates readily into cross-coupling protocols for constructing complex heterocyclic architectures under mild conditions.
5-Bromo-2-(tert-butoxy)pyridine serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient access to functionalized pyridine scaffolds. The tert-butoxy group provides excellent stability and facilitates selective derivatization, while the bromide supports reliable Suzuki, Stille, and Negishi couplings. Its bench-stable nature and compatibility with diverse reaction conditions make it ideal for medicinal chemistry and process development workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: