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Structure of 849934-95-8
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Methyl 2-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetate features a boronate ester group enabling efficient Suzuki-Miyaura coupling under mild conditions. The molecule integrates a chlorinated aryl moiety and a methyl ester handle, offering versatility in late-stage functionalization. Bench-stable and moisture-tolerant, it streamlines synthesis of complex biaryl architectures.
Methyl 2-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetate serves as a versatile boron-containing building block for palladium-catalyzed cross-coupling reactions. The pendant chlorophenyl group enables efficient Suzuki-Miyaura coupling, while the ester functionality offers synthetic handle for downstream transformations. The stable boronate ester resists protodeboronation and facilitates purification, making it well-suited for iterative synthesis of complex biaryl scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: