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CS-W001157 4
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tert-Butyl 4-oxospiro[chroman-2,4'-piperidine]-1'-carboxylate

  • CAS No. 849928-22-9

  • Cat. No. CS-0007679
  • Purity≥97%
  • MDL No.MFCD05861626

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 4-oxospiro[chroman-2,4'-piperidine]-1'-carboxylate|CS-0007679

Structure of 849928-22-9

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General Information

  • CAS No. 849928-22-9
  • Cat. No. CS-0007679
  • Purity ≥97%
  • MDL No. MFCD05861626
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₂₃NO₄
  • Molecular Weight 317.38
  • Synonym(s) tert-butyl 4-oxospiro[chromane-2,4'-piperidine]-1'-carboxylate
  • SMILES O=C(N1CCC2(CC1)CC(C3=CC=CC=C3O2)=O)OC(C)(C)C

Synthesis

  • Route1
    • null|null
      79099-07-3
    • 2'-Hydroxyacetophenone Paracetamol Impurity|CS-0228947
      118-93-4
    • ~93%
    • In-stock
      tert-Butyl 4-oxospiro[chroman-2,4'-piperidine]-1'-carboxylate|CS-0007679
      849928-22-9

    References

    • Chandrasekhar; Vijeender; Venkatram Reddy Tetrahedron Letters, 2005 , vol. 46, # 41 p. 6991 - 6993
  • Route2

    References

    • PFIZER PRODUCTS INC. Patent: WO2008/65508 A1, 2008 ; Location in patent: Page/Page column 21 ;
  • Route3
    • In-stock
      Benzophenone|CS-0015323
      119-61-9
    • null|null
      79099-07-3
    • ~%
    • In-stock
      tert-Butyl 4-oxospiro[chroman-2,4'-piperidine]-1'-carboxylate|CS-0007679
      849928-22-9

    References

    • WO2011/11872 A1, ; Page/Page column 49 ; WO 2011/011872 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.84
  • LogP   3.4215
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   0

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