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Structure of 849203-60-7
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tert-Butyl 1-oxo-7-azaspiro[3.5]nonane-7-carboxylate is a sterically shielded spirocyclic ketone bearing a bench-stable tert-butyl ester handle. This scaffold integrates a rigid, electron-deficient lactam core with enhanced solubility in organic media. It enables efficient access to complex nitrogen-containing heterocycles via modular transformations under standard conditions.
tert-Butyl 1-oxo-7-azaspiro[3.5]nonane-7-carboxylate serves as a versatile spirocyclic scaffold for medicinal chemistry and synthetic methodology development. The protected ketone and tertiary amine functionalities enable selective transformations, including reductive amination and nucleophilic addition, while the tert-butyl ester facilitates straightforward deprotection under mild acidic conditions. Its rigid, three-dimensional structure enhances binding selectivity in target-directed synthesis and supports efficient route optimization in multi-step sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: