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CS-W001157 4
Total: USD 88.00

4-Methylquinolin-2-ol

  • CAS No. 84909-43-3

  • Cat. No. CS-0097736
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Methylquinolin-2-ol|CS-0097736

Structure of 84909-43-3

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General Information

  • CAS No. 84909-43-3
  • Cat. No. CS-0097736
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₉NO
  • Molecular Weight 159.18
  • Synonym(s) None
  • SMILES OC1=NC2=CC=CC=C2C(C)=C1

Description

4-Methylquinolin-2-ol features a fused quinoline core with a methyl group at the 4-position and a phenolic hydroxyl at the 2-position, delivering enhanced solubility and stability. This scaffold integrates readily into pharmaceutical intermediates and ligands for transition metal catalysis.

Application

4-Methylquinolin-2-ol serves as a versatile building block in medicinal chemistry, enabling efficient access to quinoline-based scaffolds through standard functional group transformations. Its bench-stable nature and compatibility with palladium-catalyzed cross-coupling reactions facilitate rapid diversification. The phenolic hydroxyl group supports direct derivatization, while the methyl substituent enhances metabolic stability in target molecules.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   2.24882
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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