Lot numbers can be found on the outside label of a product:
Fmoc-FF
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CAS No. 84889-09-8
- Cat. No. CS-0030795
- Purity≥97%
- MDL No.MFCD00237669
*For research and further manufacturing use only, not for direct human use.
Structure of 84889-09-8
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General Information
- CAS No. 84889-09-8
- Cat. No. CS-0030795
- Purity ≥97%
- MDL No. MFCD00237669
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₃₃H₃₀N₂O₅
- Molecular Weight 534.60
- Synonym(s) None
- SMILES O=C([C@@H](NC([C@@H](NC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O)CC4=CC=CC=C4)=O)CC5=CC=CC=C5)O
Description
Fmoc-Phe-Phe-OH is a dipeptide building block featuring two phenylalanine residues linked by a peptide bond, with the N-terminus protected by a 9-fluorenylmethoxycarbonyl (Fmoc) group. This configuration enables efficient solid-phase peptide synthesis, offering excellent solubility and stability under standard conditions. The Fmoc protection allows for selective deprotection during iterative coupling steps.
Application
Fmoc-Phe-Phe-OH serves as a key dipeptide building block in solid-phase peptide synthesis, offering robust N-terminal protection via the fluorenylmethoxy (Fmoc) group and orthogonal deprotection compatibility. The phenylalanine side chains provide structural rigidity and hydrophobic character, facilitating efficient coupling and purification. This compound enables reliable construction of bioactive peptides and peptidomimetics with high yield and reproducibility.
Synthesis
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Route1
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474316-98-8 - ~9%
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In-stock
84889-09-8
References
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Voelkert, Martin; Koul, Surrinder; Mueller, Gernot H.; Lehnig, Manfred; Waldmann, Herbert Journal of Organic Chemistry, 2002 , vol. 67, # 20 p. 6902 - 6910
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Route2
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In-stock
35661-40-6 - ~%
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In-stock
84889-09-8
References
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Verardo; Gorassini Journal of Peptide Science, 2013 , vol. 19, # 5 p. 315 - 324
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Route3
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63-91-2 -
71989-30-5
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In-stock
84889-09-8
References
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Gagnon, Paul; Huang, Xicai; Therrien, Eric; Keillor, Jeffrey W. Tetrahedron Letters, 2002 , vol. 43, # 43 p. 7717 - 7719
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Quality Control
Computational Chemistry Data
- TPSA 104.73
- LogP 4.9485
- H_Acceptors 4
- H_Donors 3
- Rotatable_Bonds 10
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Key Words
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