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tert-Butyl (3-(3-aminopropoxy)propyl)carbamate

  • CAS No. 848419-01-2

  • Cat. No. CS-0614917
  • Purity≥98%
  • MDL No.MFCD30470390

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (3-(3-aminopropoxy)propyl)carbamate|CS-0614917

Structure of 848419-01-2

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General Information

  • CAS No. 848419-01-2
  • Cat. No. CS-0614917
  • Purity ≥98%
  • MDL No. MFCD30470390
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₄N₂O₃
  • Molecular Weight 232.32
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NCCCOCCCN

Description

tert-Butyl (3-(3-aminopropoxy)propyl)carbamate features a protected amine group flanked by flexible aliphatic chains, enabling seamless integration into peptide conjugation and bioconjugation workflows. The tert-butyl carbamate moiety provides stable protection under standard conditions, while the terminal primary amine facilitates efficient coupling reactions. This structure supports modular synthesis of functionalized biomolecules with enhanced solubility and handling convenience.

Application

tert-Butyl (3-(3-aminopropoxy)propyl)carbamate serves as a versatile bifunctional building block, enabling efficient incorporation of both amine and ether functionalities in synthetic sequences. The tert-butyl carbamate group provides stable protection for primary amines under standard conditions, while the terminal aminoether moiety facilitates downstream conjugation or cyclization reactions. This compound exhibits excellent bench stability, ease of purification, and compatibility with diverse reaction environments, making it well-suited for peptide derivatization, macrocyclization, and the construction of complex heterocyclic scaffolds in medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   73.58
  • LogP   1.2666
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   7

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