2,4-Dichloro-5,7-dihydrofuro[3,4-d]pyrimidine

Name: 2,4-Dichloro-5,7-dihydrofuro[3,4-d]pyrimidine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 848398-41-4
Cat. No. CS-W018708
Purity≥96%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2,4-Dichloro-5,7-dihydrofuro[3,4-d]pyrimidine|CS-W018708

Structure of 848398-41-4

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 848398-41-4
Cat. No. CS-W018708
Purity ≥96%
MDL No. None
Storage -20°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₄Cl₂N₂O
Molecular Weight 191.02
Synonym(s) 2,4-dichloro-5H,7H-furo[3,4-d]pyrimidine
SMILES ClC1=C2C(COC2)=NC(Cl)=N1

Description

2,4-Dichloro-5,7-dihydrofuro[3,4-d]pyrimidine is a heterocyclic scaffold featuring fused furan and pyrimidine rings with strategically positioned chlorine substituents. This electron-deficient core integrates readily into synthetic routes for pharmaceutical intermediates, offering enhanced reactivity in nucleophilic substitution processes under mild conditions.

Application

2,4-Dichloro-5,7-dihydrofuro[3,4-d]pyrimidine serves as a versatile building block for the synthesis of bioactive heterocycles, enabling efficient access to fused pyrimidine scaffolds via nucleophilic substitution. Its dichloro functionality facilitates regioselective coupling with amines and thiols under mild conditions, offering high bench stability and compatibility with diverse functional groups. This compound functions as a key intermediate in the construction of pharmaceutically relevant frameworks, particularly in kinase inhibitor and antiviral agent development.

Synthesis

Route1
- 848398-40-3
- ~47%
- In-stock
  
  848398-41-4
References
- ZHOU, Han-Jie; PARLATI, Francesco; WUSTROW, David Patent: WO2014/15291 A1, 2014 ; Location in patent: Page/Page column 181; 182 ;
Route2
- In-stock
  
  89898-51-1
- ~%
- In-stock
  
  848398-41-4
References
- WO2014/15291 A1, ;

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 35.01
LogP 1.8136
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Key Words

848398-41-4 sigma848398-41-4 manufacturer848398-41-4 price848398-41-4 structure848398-41-4 SDSbuy 848398-41-4848398-41-4 supplier848398-41-4 uses848398-41-4 molecular weightprice of 848398-41-4848398-41-4 chemical name formula of 848398-41-4

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2,4-Dichloro-5,7-dihydrofuro[3,4-d]pyrimidine

CAS No. 848398-41-4

Recommended Products