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CS-W001157 4
Total: USD 88.00

(S)-2-(Methylamino)-3-phenylpropan-1-ol

  • CAS No. 84773-29-5

  • Cat. No. CS-0151245
  • Purity≥98%
  • MDL No.MFCD18431682

*For research and further manufacturing use only, not for direct human use.

(S)-2-(Methylamino)-3-phenylpropan-1-ol|CS-0151245

Structure of 84773-29-5

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General Information

  • CAS No. 84773-29-5
  • Cat. No. CS-0151245
  • Purity ≥98%
  • MDL No. MFCD18431682
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₅NO
  • Molecular Weight 165.23
  • Synonym(s) N-Methyl-L-phenylalaninol
  • SMILES CN[C@@H](CC1=CC=CC=C1)CO

Description

(S)-2-(Methylamino)-3-phenylpropan-1-ol features a chiral center at the C2 position, delivering enantioselective reactivity in medicinal chemistry applications. The pendant phenyl group imparts aromatic character and π-stacking potential, while the primary alcohol enables derivatization. This configuration supports structural mimicry of biologically active amines, enhancing target engagement in CNS-directed drug discovery.

Application

(S)-2-(Methylamino)-3-phenylpropan-1-ol serves as a key chiral building block in the synthesis of β-arylethanolamine derivatives. Its well-defined stereochemistry enables reliable incorporation into pharmaceutically relevant scaffolds, including adrenergic receptor ligands. The molecule exhibits bench stability, tolerates common functional groups, and facilitates straightforward purification. It functions effectively in amine alkylation, reduction, and coupling reactions, making it a practical intermediate for medicinal chemistry campaigns requiring enantiopure arylalkylamines.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3259
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   32.26
  • LogP   0.8094
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   4

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