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CS-W001157 4
Total: USD 88.00

4-Bromo-2,3-dihydro-1H-inden-2-one

  • CAS No. 846032-36-8

  • Cat. No. CS-0051004
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Bromo-2,3-dihydro-1H-inden-2-one|CS-0051004

Structure of 846032-36-8

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General Information

  • CAS No. 846032-36-8
  • Cat. No. CS-0051004
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇BrO
  • Molecular Weight 211.06
  • Synonym(s) 4-Bromo-2-Indanone
  • SMILES BrC1=C2CC(CC2=CC=C1)=O

Description

4-Bromo-2,3-dihydro-1H-inden-2-one features a brominated indenone core with enhanced reactivity at the ketone and olefinic sites. This bench-stable compound integrates readily into transition-metal-catalyzed coupling reactions, enabling efficient access to functionalized indene derivatives in synthetic organic chemistry workflows.

Application

4-Bromo-2,3-dihydro-1H-inden-2-one serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted indene scaffolds. Its bromine substituent facilitates palladium-catalyzed cross-coupling reactions, while the ketone functionality supports nucleophilic additions and enolate chemistry. The compound exhibits good bench stability and is compatible with a range of functional groups, making it well-suited for iterative synthesis strategies in medicinal chemistry and materials science applications.

Synthesis

  • Route1

    References

    • WO2010/42475 A1, ; Page/Page column 99 ; WO 2010/042475 A1
  • Route2
    • null|null
      125114-82-1
    • ~%
    • In-stock
      4-Bromo-2,3-dihydro-1H-inden-2-one|CS-0051004
      846032-36-8

    References

    • WO2010/42475 A1, ; Page/Page column 100 ; WO 2010/042475 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.1168
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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