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CS-W001157 4
Total: USD 88.00

Boc-3-fluoro-4-oxopyrrolidine

  • CAS No. 845894-03-3

  • Cat. No. CS-W001654
  • Purity≥95%
  • MDL No.MFCD08274459
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Boc-3-fluoro-4-oxopyrrolidine|CS-W001654

Structure of 845894-03-3

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Description

Boc-3-fluoro-4-oxopyrrolidine features a fluorinated pyrrolidinone core with a robust Boc protecting group, enabling stable incorporation into complex molecular architectures. This scaffold delivers enhanced metabolic stability and improved membrane permeability in bioactive molecule design.

Application

Boc-3-fluoro-4-oxopyrrolidine serves as a versatile building block for the synthesis of fluorinated pyrrolidine scaffolds prevalent in medicinal chemistry. The Boc group provides stability and ease of deprotection, while the 3-fluoro and 4-oxo functionalities enable site-specific functionalization via nucleophilic addition or reductive amination. Its bench-stable nature and compatibility with standard coupling protocols facilitate efficient incorporation into complex molecular architectures.

General Information

  • CAS No. 845894-03-3
  • Cat. No. CS-W001654
  • Purity ≥95%
  • MDL No. MFCD08274459
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₄FNO₃
  • Molecular Weight 203.21
  • Synonym(s) tert-Butyl 3-fluoro-4-oxopyrrolidine-1-carboxylate
  • SMILES O=C1CN(CC1F)C(=O)OC(C)(C)C

Computational Chemistry Data

  • TPSA   46.61
  • LogP   1.1443
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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