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Structure of 84452-98-2
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2,2-Difluoroacetohydrazide features a highly polarized carbonyl group flanked by two fluorine atoms, enhancing electrophilicity for selective hydrazide coupling reactions. This bench-stable reagent integrates readily into bioconjugation workflows and serves as a key intermediate in the synthesis of fluorinated heterocycles and targeted therapeutics.
2,2-Difluoroacetohydrazide serves as a versatile building block in synthetic organic chemistry, enabling the construction of fluorinated heterocycles and functionalized hydrazones. Its difluoromethyl group imparts enhanced metabolic stability and modulates electronic properties, facilitating downstream transformations such as cyclizations and nucleophilic additions. The compound exhibits excellent bench stability and compatibility with common reaction conditions, simplifying purification and integration into multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS02,GHS07
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Signal Word : Danger
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UN#: 1325
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Class : 4.1
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Packing Group : Ⅱ
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Hazard Statements : H228-H302-H315-H319-H335
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Precautionary Statements : P210-P240-P241-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: