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CS-W001157 4
Total: USD 88.00

4'-Trifluoromethyl-2-biphenyl carboxylic acid

  • CAS No. 84392-17-6

  • Cat. No. CS-0022404
  • Molecule weight266.22
  • Purity≥97%
  • MDL No.MFCD00075353

*For research and further manufacturing use only, not for direct human use.

4'-Trifluoromethyl-2-biphenyl carboxylic acid|CS-0022404

Structure of 84392-17-6

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General Information

  • CAS No. 84392-17-6
  • Cat. No. CS-0022404
  • Purity ≥97%
  • MDL No. MFCD00075353
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₉F₃O₂
  • Molecular Weight 266.22
  • Synonym(s) None
  • SMILES O=C(C1=CC=CC=C1C2=CC=C(C(F)(F)F)C=C2)O

Description

tert-Butyl carbamate is used in palladium-catalyzed synthesis of N-Boc-protected anilines. It was used in the synthesis of tetrasubstituted pyrroles, functionalized with ester or ketone groups at C-3 position.

Synthesis

  • Route1
    • null|null
      666179-65-3
    • ~72%
    • In-stock
      4'-Trifluoromethyl-2-biphenyl carboxylic acid|CS-0022404
      84392-17-6

    References

    • SALTIGO GMBH Patent: US2012/16152 A1, 2012 ; Location in patent: Page/Page column 8 ;
  • Route2

    References

    • Korolev, Dmitrii N.; Bumagin, Nikolay A. Tetrahedron Letters, 2006 , vol. 47, # 25 p. 4225 - 4229
  • Route3
    • null|null
      84392-18-7
    • ~86%
    • In-stock
      4'-Trifluoromethyl-2-biphenyl carboxylic acid|CS-0022404
      84392-17-6

    References

    • Eaddy, III; John F. Patent: US4578522 A1, 1986 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   4.0706
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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