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CS-W001157 4
Total: USD 88.00

1,3,5-Trifluoro-2,4,6-triiodobenzene

  • CAS No. 84322-56-5

  • Cat. No. CS-W008042
  • Purity≥96%
  • MDL No.MFCD06248899

*For research and further manufacturing use only, not for direct human use.

1,3,5-Trifluoro-2,4,6-triiodobenzene|CS-W008042

Structure of 84322-56-5

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General Information

  • CAS No. 84322-56-5
  • Cat. No. CS-W008042
  • Purity ≥96%
  • MDL No. MFCD06248899
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆F₃I₃
  • Molecular Weight 509.77
  • Synonym(s) benzene, 1,3,5-trifluoro-2,4,6-triiodo-
  • SMILES FC1=C(I)C(F)=C(I)C(F)=C1I

Description

FAM (fluorescein) azide, pure 5-isomer, is a Click Chemistry labeling reagent.

Application

1,3,5-Trifluoro-2,4,6-triiodobenzene serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling the construction of complex fluorinated aromatic architectures. The strategic placement of trifluoromethyl and triiodo groups facilitates sequential functionalization via palladium-catalyzed couplings, offering high chemoselectivity and compatibility with diverse nucleophiles. Its bench-stable crystalline form simplifies handling and purification, making it well-suited for iterative synthesis workflows in medicinal chemistry and materials science.

Synthesis

  • Route1
    • null|null
      372-38-3
    • ~91%
    • In-stock
      1,3,5-Trifluoro-2,4,6-triiodobenzene|CS-W008042
      84322-56-5

    References

    • European Journal of Organic Chemistry, , # 23 p. 3927 - 3935
  • Route2
    • null|null
      372-38-3
    • ~2%
    • null|null
      84322-55-4
    • In-stock
      1,3,5-Trifluoro-2,4,6-triiodobenzene|CS-W008042
      84322-56-5

    References

    • Australian Journal of Chemistry, , vol. 35, # 8 p. 1587 - 1597
  • Route3
    • null|null
      506407-82-5
    • ~%
    • In-stock
      1,3,5-Trifluoro-2,4,6-triiodobenzene|CS-W008042
      84322-56-5

    References

    • European Journal of Organic Chemistry, , # 23 p. 3927 - 3935

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   3.9177
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

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