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Structure of 842973-74-4
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This isoxazole derivative features a 2-fluorophenyl group conjugated to a carboxylic acid-functionalized isoxazole core, enabling direct integration into bioactive scaffolds. The electron-deficient isoxazole ring facilitates efficient coupling reactions, while the ortho-fluoro substitution enhances metabolic stability and modulates electronic properties for targeted interactions in medicinal chemistry applications.
3-(2-Fluorophenyl)isoxazole-5-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its ortho-fluoro substitution enhances metabolic stability and modulates electronic properties, while the carboxylic acid group facilitates direct derivatization or conjugation. The molecule exhibits excellent bench stability and is compatible with common synthetic protocols, making it well-suited for lead optimization and API intermediate development.
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GHS Pictogram :
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GHS No : GHS06,GHS08,GHS09
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H312+H332-H317-H319-H341-H351-H370-H371-H373-H410
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Precautionary Statements : P260-P261-P264-P270-P271-P272-P273-P280-P302+P352-P304+P340-P330-P362+P364-P391-P405-P501
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Lot numbers can be found on the outside label of a product: