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Structure of 842949-48-8
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4-Methylmorpholine-2-carboxylic acid features a sterically hindered morpholine core with a carboxylic acid at the 2-position, enabling direct incorporation into peptide backbones or bioconjugation strategies. The methyl group enhances lipophilicity and metabolic stability, while the cyclic amine provides a rigid scaffold ideal for structural probing in medicinal chemistry. This compound serves as a key building block for constrained peptidomimetics and kinase inhibitor scaffolds.
4-Methylmorpholine-2-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and peptide mimetics. Its constrained morpholine core provides enhanced metabolic stability and favorable solubility, while the carboxylic acid functionality facilitates direct coupling or derivatization in standard amide bond formation protocols. The molecule exhibits excellent bench stability and is compatible with diverse functional groups, making it well-suited for iterative synthetic campaigns and scale-up applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: