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CS-W001157 4
Total: USD 88.00

4-Iodo-N-methylaniline hydrochloride

  • CAS No. 84250-74-8

  • Cat. No. CS-0162635
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Iodo-N-methylaniline hydrochloride|CS-0162635

Structure of 84250-74-8

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General Information

  • CAS No. 84250-74-8
  • Cat. No. CS-0162635
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉ClIN
  • Molecular Weight 269.51
  • Synonym(s) 4-iodo-N-methyl-aniline hydrochloride
  • SMILES CNC1=CC=C(I)C=C1.[H]Cl

Description

4-Iodo-N-methylaniline hydrochloride offers a stable, moisture-tolerant platform for cross-coupling reactions. The iodine moiety enables efficient Pd-catalyzed transformations, while the N-methyl group enhances solubility and electronic modulation. This bench-stable salt simplifies handling in synthetic workflows.

Application

4-Iodo-N-methylaniline hydrochloride serves as a versatile building block in cross-coupling reactions, enabling efficient Suzuki and Buchwald-Hartwig transformations. Its iodine functionality provides high reactivity with palladium catalysts, while the N-methyl aniline moiety offers enhanced solubility and stability under standard reaction conditions. The hydrochloride salt form improves crystallinity and handling, facilitating purification and consistent performance in synthetic workflows targeting pharmaceutical intermediates and functional materials.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Computational Chemistry Data

  • TPSA   12.03
  • LogP   2.7547
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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