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CS-W001157 4
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2-Amino-N-(p-tolyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide

  • CAS No. 83822-35-9

  • Cat. No. CS-0281370
  • Molecule weight286.39
  • Purity95+%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Amino-N-(p-tolyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide|CS-0281370

Structure of 83822-35-9

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General Information

  • CAS No. 83822-35-9
  • Cat. No. CS-0281370
  • Purity 95+%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₁₈N₂OS
  • Molecular Weight 286.39
  • Synonym(s) 2-amino-N-(4-methylphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
  • SMILES CC1=CC=C(C=C1)NC(=O)C2=C(N)SC3=C2CCCC3

Synthesis

  • Route1
    • null|null
      89733-16-4
    • ~51%
    • 2-Amino-N-(p-tolyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide|CS-0281370
      83822-35-9

    References

    • Schellhase; Bohm; Pech Pharmazie, 1984 , vol. 39, # 1 p. 19 - 21
  • Route2
    • 2-Cyano-N-(4-methylphenyl)acetamide|CS-0218546
      6876-54-6
    • null|null
      108-94-1
    • ~92%
    • 2-Amino-N-(p-tolyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide|CS-0281370
      83822-35-9

    References

    • Huang, Wei; Li, Jian; Tang, Jing; Liu, Hong; Shen, Jianhua; Jiang, Hualiang Synthetic Communications, 2005 , vol. 35, # 10 p. 1351 - 1357
  • Route3
    • 2-Cyano-N-(4-methylphenyl)acetamide|CS-0218546
      6876-54-6
    • ~%
    • 2-Amino-N-(p-tolyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide|CS-0281370
      83822-35-9

    References

    • Manjunath, Kadthala Shekar; Mohan, Shamanna; Naragund, Laxmi Venkatesh Gurachar; Shishoo, Chamanlal Jagannath Arzneimittel-Forschung/Drug Research, 1997 , vol. 47, # 9 p. 1005 - 1008

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.12
  • LogP   3.76982
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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