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CS-W001157 4
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(2S,4R)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylic acid

  • CAS No. 83624-01-5

  • Cat. No. CS-0138515
  • Molecule weight245.27
  • Purity≥97%
  • MDL No.MFCD11847488

*For research and further manufacturing use only, not for direct human use.

(2S,4R)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylic acid|CS-0138515

Structure of 83624-01-5

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General Information

  • CAS No. 83624-01-5
  • Cat. No. CS-0138515
  • Purity ≥97%
  • MDL No. MFCD11847488
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₉NO₅
  • Molecular Weight 245.27
  • Synonym(s) (4R)-1-Boc-4-methoxy-L-proline
  • SMILES O=C([C@H]1N(C(OC(C)(C)C)=O)C[C@H](OC)C1)O

Synthesis

  • Route1
    • In-stock
      Boc-Hyp-OH|CS-M3078
      13726-69-7
    • null|null
      74-88-4
    • ~65%
    • In-stock
      (2S,4R)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylic acid|CS-0138515
      83624-01-5

    References

    • Bristol-Myers Squibb Company Patent: US2007/232679 A1, 2007 ; Location in patent: Page/Page column 11 ; US 20070232679 A1
  • Route2

    References

    • DAIICHI PHARMACEUTICAL CO., LTD. Patent: EP1757602 A1, 2007 ;
  • Route3
    • (2S,4R)-1-tert-Butyl 2-methyl 4-methoxypyrrolidine-1,2-dicarboxylate|CS-0532291
      426844-31-7
    • ~99%
    • In-stock
      (2S,4R)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylic acid|CS-0138515
      83624-01-5

    References

    • Chiba, Jun; Takayama, Gensuke; Takashi, Tohru; Yokoyama, Mika; Nakayama, Atsushi; Baldwin, John J.; McDonald, Edward; Moriarty, Kevin J.; Sarko, Christopher R.; Saionz, Kurt W.; Swanson, Robert; Hussain, Zahid; Wong, Angela; MacHinaga, Nobuo Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 8 p. 2725 - 2746

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   76.07
  • LogP   1.0954
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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