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CS-W001157 4
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(2S,4S)-4-Benzyl-1-(tert-Butoxycarbonyl)pyrrolidine-2-carboxylicacid

  • CAS No. 83623-78-3

  • Cat. No. CS-0171719
  • Molecule weight305.37
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(2S,4S)-4-Benzyl-1-(tert-Butoxycarbonyl)pyrrolidine-2-carboxylicacid|CS-0171719

Structure of 83623-78-3

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General Information

  • CAS No. 83623-78-3
  • Cat. No. CS-0171719
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₂₃NO₄
  • Molecular Weight 305.37
  • Synonym(s) (4S)-1-Boc-4-benzyl-L-proline
  • SMILES CC(C)(C)OC(=O)N1C[C@@H](CC2=CC=CC=C2)C[C@H]1C(=O)O

Synthesis

  • Route1
    • 1-(tert-Butyl)2-ethyl(2s,4s)-4-benzylpyrrolidine-1,2-dicarboxylate|CS-0172984
      170947-82-7
    • ~90%
    • (2S,4S)-4-Benzyl-1-(tert-Butoxycarbonyl)pyrrolidine-2-carboxylicacid|CS-0171719
      83623-78-3

    References

    • Tian, Xinrong; Field, Timothy; Mazur, Adam W.; Ebetino, Frank H.; Wos, John A.; Crossdoersen, Doreen; Pinney, Beth B.; Sheldon, Russell J. Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 11 p. 2819 - 2823
  • Route2

    References

    • Journal of Organic Chemistry, , vol. 68, # 10 p. 3923 - 3931
  • Route3

    References

    • Journal of Organic Chemistry, , vol. 68, # 10 p. 3923 - 3931

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   66.84
  • LogP   2.9393
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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