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CS-W001157 4
Total: USD 88.00

2-(Dichloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

  • CAS No. 83622-41-7

  • Cat. No. CS-0061124
  • Purity≥97%
  • MDL No.MFCD27976342

*For research and further manufacturing use only, not for direct human use.

2-(Dichloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0061124

Structure of 83622-41-7

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General Information

  • CAS No. 83622-41-7
  • Cat. No. CS-0061124
  • Purity ≥97%
  • MDL No. MFCD27976342
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₃BCl₂O₂
  • Molecular Weight 210.89
  • Synonym(s) Pinacol (Dichloromethyl)boronate
  • SMILES CC1(C)OB(OC1(C)C)C(Cl)Cl

Application

2-(Dichloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane serves as a stable, bench-ready boron building block for Suzuki-Miyaura cross-coupling reactions. The dichloromethyl group enables direct functionalization and subsequent transformations, while the sterically protected dioxaborolane moiety ensures high reactivity and compatibility with diverse functional groups under standard coupling conditions.

Synthesis

  • Route1
    • In-stock
      2,3-Dimethylbutane-2,3-diol|CS-0015356
      76-09-5
    • null|null
      62260-98-4
    • ~%
    • In-stock
      2-(Dichloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0061124
      83622-41-7

    References

    • Raheem, Izzat T.; Goodman, Steven N.; Jacobsen, Eric N. Journal of the American Chemical Society, 2004 , vol. 126, # 3 p. 706 - 707

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1760
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H314
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P330-P363-P405-P501

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Computational Chemistry Data

  • TPSA   18.46
  • LogP   2.4215
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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