N-(2-Bromopyridin-3-yl)pivalamide

Name: N-(2-Bromopyridin-3-yl)pivalamide
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 835882-02-5
Cat. No. CS-0179632
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

N-(2-Bromopyridin-3-yl)pivalamide|CS-0179632

Structure of 835882-02-5

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 835882-02-5
Cat. No. CS-0179632
Purity ≥98%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₃BrN₂O
Molecular Weight 257.13
Synonym(s) N-(2-bromopyridin-3-yl)trimethylacetamide
SMILES CC(C)(C)C(NC1=CC=CN=C1Br)=O

Description

N-(2-Bromopyridin-3-yl)pivalamide features a sterically shielded pivaloyl group attached to a bromopyridine nitrogen, enhancing stability and facilitating selective functionalization. This bench-stable derivative enables direct coupling in transition-metal-catalyzed cross-coupling reactions, serving as a robust building block for complex heterocyclic architectures in medicinal chemistry and materials science.

Application

N-(2-Bromopyridin-3-yl)pivalamide serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, particularly in the construction of biaryl and heteroaryl scaffolds. The bromopyridine moiety enables efficient Pd-catalyzed coupling with boronic acids and other nucleophiles, while the pivalamide group provides steric protection and enhanced bench stability. Its functional group tolerance and ease of purification make it well-suited for iterative synthesis in medicinal chemistry and process development workflows.

Synthesis

Route1
- In-stock
  
  39856-58-1
- 3282-30-2
- ~90%
- In-stock
  
  835882-02-5
References
- JANSSEN PHARMACEUTICA, N.V. Patent: WO2005/9967 A2, 2005 ; Location in patent: Page/Page column 25-26 ; WO 2005/009967 A2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 41.99
LogP 2.8287
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

N-(2-Bromopyridin-3-yl)pivalamide sigmaN-(2-Bromopyridin-3-yl)pivalamide manufacturerN-(2-Bromopyridin-3-yl)pivalamide priceN-(2-Bromopyridin-3-yl)pivalamide structureN-(2-Bromopyridin-3-yl)pivalamide SDSbuy N-(2-Bromopyridin-3-yl)pivalamideN-(2-Bromopyridin-3-yl)pivalamide supplierN-(2-Bromopyridin-3-yl)pivalamide usesN-(2-Bromopyridin-3-yl)pivalamide molecular weightprice of N-(2-Bromopyridin-3-yl)pivalamideN-(2-Bromopyridin-3-yl)pivalamide chemical name formula of N-(2-Bromopyridin-3-yl)pivalamide

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

N-(2-Bromopyridin-3-yl)pivalamide

CAS No. 835882-02-5

Recommended Products