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CS-W001157 4
Total: USD 88.00

Prop-2-yn-1-yl 1H-imidazole-1-carboxylate

  • CAS No. 83395-38-4

  • Cat. No. CS-0169601
  • Purity≥95%
  • MDL No.MFCD18830798

*For research and further manufacturing use only, not for direct human use.

Prop-2-yn-1-yl 1H-imidazole-1-carboxylate|CS-0169601

Structure of 83395-38-4

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General Information

  • CAS No. 83395-38-4
  • Cat. No. CS-0169601
  • Purity ≥95%
  • MDL No. MFCD18830798
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆N₂O₂
  • Molecular Weight 150.13
  • Synonym(s) Propargyl imidazolecarbamate
  • SMILES O=C(N1C=CN=C1)OCC#C

Description

Prop-2-yn-1-yl 1H-imidazole-1-carboxylate is a versatile alkynyl-containing heterocyclic reagent designed for copper-free click chemistry. The propargyl ester moiety enables efficient conjugation with azides under mild conditions, while the imidazole carboxylate group enhances solubility and stability in aqueous environments. This reagent streamlines bioconjugation workflows and delivers high yields in protein labeling and probe synthesis.

Synthesis

  • Route1
    • null|null
      107-19-7
    • null|null
      530-62-1
    • ~87%
    • In-stock
      Prop-2-yn-1-yl 1H-imidazole-1-carboxylate|CS-0169601
      83395-38-4

    References

    • Heller, Stephen T.; Sarpong, Richmond Organic Letters, 2010 , vol. 12, # 20 p. 4572 - 4575
  • Route2
    • Imidazole Ondansetron Impurity|CS-0229601
      288-32-4
    • null|null
      35718-08-2
    • ~87%
    • In-stock
      Prop-2-yn-1-yl 1H-imidazole-1-carboxylate|CS-0169601
      83395-38-4

    References

    • Nielsen, Thorbjorn Terndrup; Wintgens, Veronique; Amiel, Catherine; Wimmer, Reinhard; Larsen, Kim Lambertsen Biomacromolecules, 2010 , vol. 11, # 7 p. 1710 - 1715

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   44.12
  • LogP   0.501
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

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