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CS-W001157 4
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1H-Imidazol-1-amine hydrochloride

  • CAS No. 83279-44-1

  • Cat. No. CS-0112886
  • Purity≥98%
  • MDL No.MFCD26390998

*For research and further manufacturing use only, not for direct human use.

1H-Imidazol-1-amine hydrochloride|CS-0112886

Structure of 83279-44-1

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General Information

  • CAS No. 83279-44-1
  • Cat. No. CS-0112886
  • Purity ≥98%
  • MDL No. MFCD26390998
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₆ClN₃
  • Molecular Weight None
  • Synonym(s) Imidazol-1-ylamine
  • SMILES NN1C=CN=C1.[H]Cl

Description

1H-Imidazol-1-amine hydrochloride offers a readily accessible nitrogen-rich scaffold for medicinal chemistry and catalyst design. This bench-stable salt features a protonated imidazole core, enhancing solubility in aqueous and polar organic media. Its amine functionality enables direct coupling or derivatization, streamlining synthesis of bioactive heterocycles and functional materials.

Application

1H-Imidazol-1-amine hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to imidazole-containing scaffolds prevalent in bioactive molecules. Its well-defined reactivity facilitates direct incorporation into peptide mimetics, kinase inhibitors, and heterocyclic drug candidates. The hydrochloride salt enhances bench stability and simplifies handling, while the primary amine functionality supports diverse coupling reactions and derivatization strategies under standard conditions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   43.84
  • LogP   0.0187
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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