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CS-W001157 4
Total: USD 88.00

N-PhenylsucciniMide

  • CAS No. 83-25-0

  • Cat. No. CS-0156126
  • Purity≥96%
  • MDL No.MFCD00022587

*For research and further manufacturing use only, not for direct human use.

N-PhenylsucciniMide|CS-0156126

Structure of 83-25-0

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General Information

  • CAS No. 83-25-0
  • Cat. No. CS-0156126
  • Purity ≥96%
  • MDL No. MFCD00022587
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₉NO₂
  • Molecular Weight 175.18
  • Synonym(s) 1-Phenyl-2,5-pyrrolidinedione
  • SMILES C1=CC=C(C=C1)N2C(=O)CCC2=O

Description

N-Phenylsuccinimide features a rigid, electron-deficient imide core paired with a phenyl substituent, enhancing its utility in cycloaddition reactions. This bench-stable compound integrates readily into synthetic pathways requiring controlled electrophilic character and offers predictable reactivity under standard conditions.

Application

N-Phenylsuccinimide serves as a stable, bench-ready acylating agent and key intermediate in the synthesis of pharmaceuticals and functional materials. It functions effectively in amide bond formation, exhibits good solubility in common organic solvents, and enables efficient derivatization under mild conditions. Its robustness and predictable reactivity make it a reliable choice for peptide coupling and heterocyclic scaffold construction in industrial and academic R&D workflows.

Synthesis

  • Route1
    • In-stock
      Succinic acid|CS-0008946
      110-15-6
    • null|null
      74497-02-2
    • ~94%
    • In-stock
      N-PhenylsucciniMide|CS-0156126
      83-25-0

    References

    • Kobeissi, Marwan; Yazbeck, Ogaritte; Chreim, Yamama Tetrahedron Letters, 2014 , vol. 55, # 15 p. 2523 - 2526
  • Route2

    References

    • Watanabe, Yoshihisa; Tsuji, Yasushi; Kondo, Teruyuki; Takeuchi, Ryo Journal of Organic Chemistry, 1984 , vol. 49, # 23 p. 4451 - 4455
  • Route3

    References

    • Lan, Jing-Bo; Zhang, Guo-Lin; Yu, Xiao-Qi; You, Jing-Song; Chen, Li; Yan, Mei; Xie, Ru-Gang Synlett, 2004 , # 6 p. 1095 - 1097

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Computational Chemistry Data

  • TPSA   37.38
  • LogP   1.34
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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