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CS-W001157 4
Total: USD 88.00

Adamantane-carboxylic acid

  • CAS No. 828-51-3

  • Cat. No. CS-W017189
  • Purity≥97%
  • MDL No.MFCD00074720

*For research and further manufacturing use only, not for direct human use.

Adamantane-carboxylic acid|CS-W017189

Structure of 828-51-3

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General Information

  • CAS No. 828-51-3
  • Cat. No. CS-W017189
  • Purity ≥97%
  • MDL No. MFCD00074720
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₆O₂
  • Molecular Weight 180.25
  • Synonym(s) None
  • SMILES OC(C12C[C@H]3C[C@@H](C2)C[C@@H](C1)C3)=O

Description

1-Adamantanecarboxylic acid can be used as: A stabilizer in the synthesis of monodisperse, highly crystalline CoPt3nanoparticles and porous platinum nanoparticles.An additive in polycondensation reactions to yield conjugated polymers as possible optoelectronic materials.An additive in the allylic substitution reaction, which is catalyzed by palladium in an aqueous medium.

Application

Adamantane-carboxylic acid serves as a robust, sterically hindered building block for medicinal chemistry and materials science. Its rigid, hydrophobic adamantane core enhances metabolic stability and lipophilicity in bioactive molecules. The carboxylic acid functionality enables straightforward derivatization via esterification, amide coupling, or salt formation, facilitating integration into diverse scaffolds. Bench-stable and easily purified by recrystallization, it functions reliably in standard synthetic workflows.

Synthesis

  • Route1
    • null|null
      64-18-6
    • In-stock
      1-Adamantanol|CS-W020580
      768-95-6
    • ~92%
    • In-stock
      Adamantane-carboxylic acid|CS-W017189
      828-51-3

    References

    • Fukuyama, Takahide; Mukai, Yu; Ryu, Ilhyong Beilstein Journal of Organic Chemistry, 2011 , vol. 7, art. no. 149, p. 1288 - 1293
  • Route2

    References

    • Daicel Chemical Industries, Ltd.; Ishii, Yasutaka Patent: EP897747 A1, 1999 ;
  • Route3
    • null|null
      201230-82-2
    • null|null
      2094-74-8
    • null|null
      77418-99-6
    • ~21%
    • In-stock
      Adamantane-carboxylic acid|CS-W017189
      828-51-3
    • null|null
      97382-21-3

    References

    • Tetrahedron, , vol. 43, # 4 p. 701 - 710

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.2874
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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