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CS-W001157 4
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2,3-Dichloro-5-methylquinoxaline

  • CAS No. 82463-30-7

  • Cat. No. CS-0157006
  • Molecule weight213.06
  • Purity≥97%
  • MDL No.MFCD27929282

*For research and further manufacturing use only, not for direct human use.

2,3-Dichloro-5-methylquinoxaline|CS-0157006

Structure of 82463-30-7

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General Information

  • CAS No. 82463-30-7
  • Cat. No. CS-0157006
  • Purity ≥97%
  • MDL No. MFCD27929282
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆Cl₂N₂
  • Molecular Weight 213.06
  • Synonym(s) 2,3-DICHLORO-5-METHYLQUINOXALINE(WXG01336)
  • SMILES C1=CC(=C2C(=C1)N=C(C(=N2)Cl)Cl)C

Description

2,3-Dichloro-5-methylquinoxaline features a sterically hindered, electron-deficient quinoxaline core that facilitates selective coupling reactions in synthetic chemistry. This bench-stable heterocycle integrates readily into advanced scaffolds for pharmaceutical intermediates and functional materials, offering high reactivity under mild conditions.

Application

2,3-Dichloro-5-methylquinoxaline serves as a versatile building block in heterocyclic synthesis, enabling efficient C–H functionalization and palladium-catalyzed cross-coupling reactions. The dichloro substitution pattern provides orthogonal reactivity for sequential derivatization, while the methyl group enhances solubility and modulates electronic properties. Its bench-stable crystalline form facilitates handling and purification, making it ideal for constructing complex quinoxaline-based scaffolds in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   25.78
  • LogP   3.24502
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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