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CS-W001157 4
Total: USD 88.00

2-Chlorocyclohexanone,98%(stabilized with HQ)

  • CAS No. 822-87-7

  • Cat. No. CS-W013402
  • Purity98%(stabilized with HQ)
  • MDL No.MFCD00001626

*For research and further manufacturing use only, not for direct human use.

2-Chlorocyclohexanone,98%(stabilized with HQ)|CS-W013402

Structure of 822-87-7

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General Information

  • CAS No. 822-87-7
  • Cat. No. CS-W013402
  • Purity 98%(stabilized with HQ)
  • MDL No. MFCD00001626
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₉ClO
  • Molecular Weight 132.59
  • Synonym(s) Cyclohexanone, 2-chloro-; 2-Chlorocyclohexanone
  • SMILES O=C1C(Cl)CCCC1

Description

2-Chlorocyclohexanone, stabilized with hydroquinone, is a bench-stable ketone featuring a chlorine substituent that enhances electrophilicity at the carbonyl carbon. This reactivity profile enables direct incorporation into synthetic sequences requiring selective functionalization. The stabilizing hydroquinone prevents unwanted polymerization during storage and handling.

Application

2-Chlorocyclohexanone serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of cyclic scaffolds via nucleophilic addition and aldol-type condensations. Its stabilized form (with hydroquinone) ensures enhanced bench stability and reproducible reactivity, facilitating reliable use in multi-step syntheses. The molecule exhibits favorable functional group tolerance and is well-suited for applications requiring controlled carbonyl reactivity in medicinal chemistry and process development workflows.

Synthesis

  • Route1
    • null|null
      4065-81-0
    • ~91%
    • In-stock
      2-Chlorocyclohexanone,98%(stabilized with HQ)|CS-W013402
      822-87-7

    References

    • Ahlsten, Nanna; Gomez, Antonio Bermejo; Martin-Matute, Belen Angewandte Chemie - International Edition, 2013 , vol. 52, # 24 p. 6273 - 6276 Angew. Chem., 2013 , vol. 125, # 24 p. 6393 - 6396,4
  • Route2

    References

    • Helvetica Chimica Acta, , vol. 12, p. 14 Chemische Berichte, , vol. 60, p. 1420
  • Route3
    • null|null
      108-94-1
    • ~%
    • null|null
      59892-15-8
    • null|null
      65933-44-0
    • In-stock
      2-Chlorocyclohexanone,98%(stabilized with HQ)|CS-W013402
      822-87-7

    References

    • Journal of Organic Chemistry, , vol. 46, # 22 p. 4486 - 4489

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: 3335
Class : 9
Packing Group : Ⅲ
Hazard Statements : H303-H315-H317-H319-H335
Precautionary Statements : P260-P261-P264-P271-P272-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   1.7369
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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