Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole

  • CAS No. 82099-98-7

  • Cat. No. CS-0053983
  • Purity≥96%
  • MDL No.MFCD12026052

*For research and further manufacturing use only, not for direct human use.

4-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole|CS-0053983

Structure of 82099-98-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 82099-98-7
  • Cat. No. CS-0053983
  • Purity ≥96%
  • MDL No. MFCD12026052
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁BrN₂O
  • Molecular Weight 231.09
  • Synonym(s) 4-BroMo-1-(tetrahydropyran-2-yl)pyrazole
  • SMILES BrC1=CN(C2CCCCO2)N=C1

Description

This pyrazole derivative features a bromine substituent at the 4-position and a tetrahydropyran-2-yl group at the 1-position, providing enhanced stability and solubility. The electron-deficient pyrazole core facilitates efficient coupling reactions, while the protecting group enables selective deprotection under mild conditions. This combination supports streamlined synthesis in medicinal chemistry applications.

Application

4-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole serves as a versatile building block in medicinal chemistry, enabling efficient late-stage functionalization via palladium-catalyzed cross-coupling reactions. The tetrahydropyran-2-yl protecting group offers excellent stability under basic and mild acidic conditions, facilitating orthogonal deprotection and simplifying purification. Its bromine substituent provides reliable reactivity in Suzuki, Stille, and Negishi couplings, making it well-suited for constructing complex heterocyclic scaffolds and diversifying molecular libraries with high reproducibility.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   27.05
  • LogP   2.3447
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 82099-98-7 sigma82099-98-7 manufacturer82099-98-7 price82099-98-7 structure82099-98-7 SDSbuy 82099-98-782099-98-7 supplier82099-98-7 uses82099-98-7 molecular weightprice of 82099-98-782099-98-7 chemical name formula of 82099-98-7
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label