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2-(2-Methoxyethoxy)benzenesulfonamide

  • CAS No. 82031-33-2

  • Cat. No. CS-0150165
  • Molecule weight231.27
  • Purity≥98%
  • MDL No.MFCD03265376

*For research and further manufacturing use only, not for direct human use.

2-(2-Methoxyethoxy)benzenesulfonamide|CS-0150165

Structure of 82031-33-2

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General Information

  • CAS No. 82031-33-2
  • Cat. No. CS-0150165
  • Purity ≥98%
  • MDL No. MFCD03265376
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃NO₄S
  • Molecular Weight 231.27
  • Synonym(s) 2-(2-Methoxyethoxy)benzen sulfonamide
  • SMILES COCCOC1=CC=CC=C1S(=O)(=O)N

Description

2-(2-Methoxyethoxy)benzenesulfonamide features a benzene ring bearing both a sulfonamide group and a polar, ether-functionalized side chain. This combination imparts enhanced solubility in aqueous and protic solvents while maintaining stability under standard bench conditions. The methoxyethoxy moiety facilitates integration into bioactive scaffolds requiring improved pharmacokinetic profiles.

Application

2-(2-Methoxyethoxy)benzenesulfonamide serves as a versatile sulfonamide building block in medicinal chemistry, offering enhanced solubility and metabolic stability. Its ortho-substituted aromatic sulfonamide moiety enables robust coupling reactions and facilitates hydrogen bonding in target binding sites. The methoxyethoxy side chain improves polarity and processability, supporting efficient purification and scalability in API synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   78.62
  • LogP   0.3592
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   5

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