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Structure of 81971-38-2
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3-Bromo-1-methyl-1,2-dihydropyridin-2-one is a bench-stable, electron-deficient heterocycle featuring a bromine substituent at the 3-position and a methyl group at nitrogen. This structure enables direct functionalization in cross-coupling reactions and serves as a key intermediate in the synthesis of bioactive pyridine derivatives.
3-Bromo-1-methyl-1,2-dihydropyridin-2-one serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted pyridones via palladium-catalyzed cross-coupling reactions. The bromine atom facilitates reliable C–C bond formation under standard Suzuki, Stille, or Negishi conditions, while the enaminone functionality supports further functionalization. Its bench-stable nature and compatibility with diverse reaction conditions make it well-suited for modular synthesis of bioactive heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: