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CS-W001157 4
Total: USD 88.00

4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one sofosbuvir Impurity

  • CAS No. 817204-33-4

  • Cat. No. CS-0167058
  • Molecule weight259.23
  • Purity≥98%
  • MDL No.MFCD13176566

*For research and further manufacturing use only, not for direct human use.

4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one sofosbuvir Impurity|CS-0167058

Structure of 817204-33-4

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General Information

  • CAS No. 817204-33-4
  • Cat. No. CS-0167058
  • Purity ≥98%
  • MDL No. MFCD13176566
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₄FN₃O₄
  • Molecular Weight 259.23
  • Synonym(s) Psi-6130
  • SMILES C[C@@]1([C@H](N2C(N=C(C=C2)N)=O)O[C@@H]([C@H]1O)CO)F

Synthesis

  • Route1
    • (2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate Sofosbuvir Impurity|CS-0229294
      817204-32-3
    • ~93%
    • 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one sofosbuvir Impurity|CS-0167058
      817204-33-4

    References

    • Carr, Robert; Hildbrand, Stefan; Hodges, Mark L.; Kammerer, Michael; Lang, John F.; Lawrimore, III, William J.; Nguyen, Dieu Patent: US2013/324709 A1, 2013 ; Location in patent: Paragraph 0053; 0054 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   110.6
  • LogP   -1.1957
  • H_Acceptors   7
  • H_Donors   3
  • Rotatable_Bonds   2

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