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Structure of 81560-03-4
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5-Bromo-2-(methylthio)pyrimidin-4(3H)-one features a brominated pyrimidinone core with a methylthio substituent at the 2-position, delivering enhanced reactivity for cross-coupling and functionalization. This bench-stable heterocycle integrates readily into synthetic pathways requiring halogen-directed derivatization or metal-catalyzed transformations.
5-Bromo-2-(methylthio)pyrimidin-4(3H)-one serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its stable bromo substituent. The methylthio group enhances solubility and facilitates selective functionalization, while the pyrimidinone core provides a rigid, hydrogen-bond-capable scaffold suitable for targeted drug discovery. Bench-stable and readily purified by recrystallization, it functions effectively in standard synthetic workflows involving nucleophilic substitution or transition-metal-mediated transformations.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: